Operator and institutional experience reduces room-to-balloon times for transradial primary percutaneous coronary intervention.

BACKGROUND Transradial (TR) access for primary percutaneous coronary intervention (PCI) is becoming accepted as the preferred approach but has not gained widespread adoption due to technical challenges that may limit procedural success and delay time to revascularization, particularly among patients treated by inexperienced operators. We report our experience over the first 2 years of our TR primary PCI program and determined the impact of TR access on clinical and procedural outcomes. METHODS Clinical characteristics and procedural outcomes were collected prospectively from 488 patients presenting with ST-segment elevation myocardial infarction and compared according to whether patients underwent primary PCI via the TR or transfemoral (TF) approach. RESULTS Hospital mortality was very low in both groups (1.1% [TR] vs 2.6% [TF]; P=.23). Access-site intended procedural success for primary PCI was equivalent (98.4% for TR vs 98.6% for TF; P=.85). Catheterization room-to-balloon (RTB) times were significantly lower among patients undergoing TR primary PCI as compared with those in the TF group (20:33 ± 06:41 [TR] vs 25:11 ± 08:22 [TF]; P<.001). TR patients treated by operators who had performed >50 TR PCIs had lower RTB times (20:03 ± 06:12 vs 24:26 ± 10:01; P<.06) and lower doses of radiation exposure (1812 ± 1007 mGy vs 2827 ± 954 mGy; P<.01) than patients treated by less experienced operators. Dual-purpose guide catheter usage was also associated with lower RTB times (18:38 ± 5:42 vs 25:15 ± 8:20; P<.001) and radiation exposure (1824 ± 6205 mGy vs 2407 ± 1389 mGy; P<.01). CONCLUSIONS TR primary PCI may be performed rapidly and successfully despite only modest operator and institutional experience.